Endometrial Biopsy Specialist in Columbia, MD and Greenbelt, MD
An endometrial biopsy involves collecting a small tissue sample from the uterine lining for examination. It is often used to investigate abnormal bleeding, hormonal imbalances, or to rule out uterine cancer. The procedure is minimally invasive, typically performed in a doctor’s office. At Women’s Wellness MD, Dr. Chetanna Okasi, MD, a Board-Certified OB-GYN, and her team offer skilled care in performing this procedure to ensure accurate diagnosis and personalized treatment options. For more information, contact us or request an appointment online. We have convenient locations to serve you in Columbia, MD & Greenbelt, MD.


Table of Contents:
What is an endometrial biopsy?
What are the benefits of an endometrial biopsy?
How long does it take to recover from an endometrial biopsy?
What happens if your endometrial biopsy is positive?
An endometrial biopsy is a medical procedure used to collect a small sample of tissue from the lining of the uterus (endometrium) for examination. This test is typically performed to investigate abnormal uterine bleeding, rule out conditions like cancer or infections, or evaluate hormonal imbalances. It is often recommended for women experiencing irregular periods, postmenopausal bleeding, or other unexplained symptoms.
During the procedure, a healthcare provider uses a thin, flexible tube (catheter) inserted into the uterus through the cervix to remove a small tissue sample. The procedure is usually done in a doctor’s office and may cause mild cramping or discomfort, although local anesthesia is often used to minimize pain. The sample is then sent to a laboratory for analysis, where pathologists examine the tissue under a microscope to look for abnormalities such as cancer, infection, or signs of endometrial hyperplasia (an overgrowth of the uterine lining).
An endometrial biopsy is a valuable tool for diagnosing various conditions, helping guide treatment options, and providing important information about reproductive health. While the procedure is relatively quick and minimally invasive, it may be recommended based on a patient’s specific symptoms or medical history.
At Women’s Wellness MD, we are committed to providing comprehensive and compassionate care for every stage of a woman’s life. One important service we offer is the endometrial biopsy, a valuable tool in evaluating and managing your gynecological health.
An endometrial biopsy involves taking a small sample of tissue from the lining of your uterus (the endometrium). This simple, in-office procedure helps our providers accurately diagnose the cause of abnormal uterine bleeding—a concern that affects many women both before and after menopause. By examining the tissue under a microscope, we can detect conditions such as endometrial hyperplasia (an overgrowth of the uterine lining) or even endometrial cancer in its earliest, most treatable stages.
An endometrial biopsy also plays a vital role for women experiencing infertility or those undergoing hormone therapy. By analyzing how your endometrial lining responds to hormonal changes, we can better understand your reproductive health and tailor your treatment, whether you are trying to conceive or managing symptoms with hormones.
Our experienced specialists perform this minimally invasive procedure right in our comfortable office setting. Most women return to their normal activities shortly afterward.
The results of your endometrial biopsy enable our Women’s Wellness MD team to create a personalized and effective treatment plan, ensuring you get the most appropriate care, right when you need it. Your health and peace of mind are always our top priorities.
If you have concerns about abnormal bleeding, infertility, or hormone therapy, schedule a consultation today to learn if an endometrial biopsy could benefit you.
At Women’s Wellness MD, your comfort and health are our top priorities. Most women recover quickly following an endometrial biopsy performed in our clinic. It’s common to experience mild cramping, similar to menstrual cramps, and light spotting after the procedure. These symptoms typically resolve within a few hours to a couple of days. In most cases, our patients are able to return to their regular activities the same day or by the next day.
To support your recovery and reduce the risk of infection, we recommend avoiding tampons, douching, and sexual intercourse for a few days after your biopsy, or as advised by your provider. If you experience any heavy bleeding, severe pain, fever, or notice a foul-smelling vaginal discharge, please contact our office immediately—these symptoms may indicate a complication that requires prompt attention.
Rest assured, most women have a smooth recovery with minimal disruption to their daily routines. Our team at Women’s Wellness MD will provide you with detailed post-procedure instructions tailored to your individual needs. If you have any questions or concerns during your recovery, don’t hesitate to reach out to us—we’re here to support you every step of the way.
At Women’s Wellness MD, we understand that receiving a positive endometrial biopsy result can be concerning. A positive result means that your tissue sample—taken from the lining of your uterus (endometrium)—showed some abnormal changes. The exact meaning depends on the specific type of abnormality detected.
For example, your biopsy may reveal:
• Endometrial hyperplasia: A thickening of the uterine lining, which can occasionally be a precursor to uterine cancer.
• Endometrial cancer: The presence of cancerous cells in the uterine lining.
• Other conditions: Such as uterine polyps or chronic inflammation.
When a positive result is identified, our team will thoroughly review your findings and discuss them with you in detail. If the results show precancerous changes, like atypical hyperplasia, or cancerous cells, we may recommend additional testing or treatment.
This could include imaging studies, blood tests, or surgical options, depending on the severity of the findings. For less severe abnormalities, hormonal therapy or careful monitoring with repeat biopsies may be appropriate.
It’s important to remember that a positive endometrial biopsy does not always mean cancer. However, it does indicate a need for further evaluation to prevent the potential progression of disease. At Women’s Wellness MD, we personalize your care plan based on your individual risk factors, overall health, and specific biopsy results.
Timely follow-up and adhering to your provider’s recommendations are essential for achieving the best possible outcome. Our compassionate team is here to support you every step of the way, ensuring you receive the highest level of care for your health. For more information, contact us or request an appointment online. We have convenient locations to serve you in Columbia, MD & Greenbelt, MD. We serve patients from Columbia MD, Greenbelt MD, Ellicott City MD, Jessup MD, Savage MD, New Carrollton MD, College Park MD, Beltsville MD, Bowie MD, and surrounding areas.

Additional Services You May Need
▸ Breast Cancer Screening
▸ Cervical Cancer Screening
▸ Endometrial Biopsy
▸ Cervical Biopsy
▸ Ultrasound
▸ Colposcopy
▸ Annual Well Women’s Exams
▸ Urinary Tract Infection
▸ Hot Flashes

Additional Services You May Need
▸ Breast Cancer Screening
▸ Cervical Cancer Screening
▸ Endometrial Biopsy
▸ Cervical Biopsy
▸ Ultrasound
▸ Colposcopy
▸ Annual Well Women’s Exams
▸ Urinary Tract Infection
▸ Sexually Transmitted Disease
▸ Pelvic Pain
▸ Semaglutide GLP-1
▸ Tirzepatide
▸ Medical Weight Loss
▸ Irregular Menstrual Bleeding
▸ Heavy Periods
▸ Menopause
▸ Fibroids
▸ Bladder Problems
▸ Bioidentical Hormone Replacement Therapy
▸ Infertility
▸ Family Planning
▸ Botox
▸ Sexual Health
▸ Hot Flashes
▸ Polycystic Ovary Syndrome (PCOS)